Metrum Institute

Metrum Institute Training Courses

Metrum Institute has expanded its training program for 2008. Many new courses are offered, and some of our most popular courses are restructured. Course outlines are offered below.

Want to view all of our current courses at a glance? Click here for PDF version.

Course # Course Title Dates Location Cost*
Outline
Registration

MI120-W

new sections added!

Brief Introduction to R and MItools
MI120 is a brief, but intensive hands-on introduction to the R language, with specific focus on functions and features useful in pharmacometrics. This course also includes an introduction to the MItools package, which is used in later courses for processing of NONMEM® runs.

Prerequisites
: none
Spring 2008: May 13 & 16
Fall 2008: Sept. 2 & 5
Spring 2009: Feb. 3 & 6
webcast
$300*
Download Course outline in PDF
MI210 Essentials of Population PKPD Modeling & Simulation
Course description is same as MI210-W, below, but course is held on location at The Children's Hospital of Philadelphia.

Click here for a list of suggested hotels and area map.

May 19-21, 2008
9:00AM-5:00PM Eastern time

Wanamaker Bldg
7th Floor
Room 7102
100 Penn Square E
Philadelphia, PA
$2475*
download outline in pdf
Closed-Registration Full
MI210-W
Essentials of Population PKPD Modeling & Simulation
MI210 provides an extensive overview of essential topics in population pharmacokinetics and pharmacodynamics, including: nonlinear-mixed effects modeling theory and implementation, data formatting requirements, population model development, model evaluation techniques, continuous PK-PD models, Monte Carlo simulation, and best practices. Instruction combines didactic lectures with hands-on exercises using R and the NONMEM® software.

Prerequisites:
Basic understanding of pharmacokinetic and pharmacodynamic principles, compartmental pharmacokinetic models, introductory statistics, familiarity with the R or S language. Applicable MI Courses include: MI120, MI101, MI201, or contact instructor.

Fall: Sept. 9-Dec. 12, 2008 webcast
$3000*
download outline in pdf
MI212-W
Advanced Topics in Population PK-PD Modeling & Simulation
MI212 extends the material inititated in MI210 including a detailed overview of advanced topics in population pharmacokinetics and pharmacodynamics: inter-occasion variability, mixture models, truncated continuous data (BQL), nonlinear-pharmacokinetic models, models for parent & metabolite plasma and urine data, indirect-response pharmacodynamic models, models for tolerance, precursor pools and complex systems, disease progression models, population PK study design, and clinical trial simulation. Instruction combines didactic lectures with hands-on exercises using R and the NONMEM® software.

Prerequisites:
MI210 and related prerequisites.
Spring: Feb. 10 - May 1, 2009 webcast $3000*
download outline in pdf
MI250 Introduction to Bayesian PK-PD Modeling & Simulation
MI250 is an intensive, 3-day onsite course that provides an introduction to Bayesian modeling and the practical use of WinBUGS and R for PK-PD applications.

Prerequisites:
Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is requred. Applicable MI courses include: MI 210 and MI212.

July 16-18, 2008 (Wed-Fri)
8:30AM-4:30PM Eastern time

The Harborside
Bar Harbor, ME

Mention Metrum Institute to receive our group rate of $219/night.

Bar Harbor area map w/ airport locations

$2475*
Download Course outline in PDF
register online now
New!
MI255 Exposure-Response Modeling of Categorical, Count and Time-to-Event Data Using Bayesian and Maximum Likelihood Methods
MI255 provides and introduction to modeling of categorical, count, and time-to-event data, and the practical use of NONMEM® and WinBUGS for such applications.

Prequisites: Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is required. Prior experience with Bayesian modeling using WinBUGS is desirable but not required. The course includes a short introduction to Bayesian principles and WinBUGS. Applicable MI courses include: MI210, MI212 and MI250, or contact instructor.

July 21-23, 2008 (Mon-Wed)
8:30AM-4:30PM Eastern time

The Harborside
Bar Harbor, ME

Mention Metrum Institute to receive our group rate of $219/night.

Bar Harbor area map w/ airport locations

$2475*
Download Course outline in PDF
register online now
New!

*Discounts are offered to academic, non-profit and government agencies. See course outlines for details.
Metrum Institute is continuously developing this curriculum. If you have any suggestions for training topics, please contact us.


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